This is important to prevent bleeding from cuts or other injuries. You can limit problems caused by low platelets by doing things that lower your risk of bleeding. Low Platelet Count Causes Symptoms And Treatment How To Diagnose The phase IV clinical study analyzes which people take Ibuprofen and have Thrombocytopenia. . Withdrawing the causative drug is the management of choice for a drug-induced low platelet count. Stopping or switching medications that affect platelets including aspirin and ibuprofen getting certain types of vaccinations avoiding toxic chemicals Complications If left untreated a low. Ibuprofen can cause gastric ulcers which can cause some bleeding which you might not be aware of and that can cause platelets to fall. Your platelet count low of 125 is most likely of no consequence. Low Platelets Platelets are the blood cells that help the body to form clots. Normal platelet counts usually range between 15